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In guinea pigs fed a high-cholesterol diet, lutein (0.1 g per 100 g) therapy prevents degenerative diseases in the liver by lowering hepatic free cholesterol, lipid peroxidation, and attenuating the inflammatory responses known to be involved in the development of non-alcoholic fatty liver disease (NAFLD) [74]

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Neutrophils play a crucial role in the early stage of nonalcoholic steatohepatitis via neutrophil elastase in mice

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However, they were also found in the cytoplasm and within the axons of the fiber tracts known to undergo neurodegeneration in this disease [29,30,31]

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